Factor H (30C-CP2038U )

Purified native Human Factor H

Synonyms Complement Factor H
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human serum/plasma
Molecular Weight 155 kDa
Form & Buffer Frozen liquid in 10mM sodium phosphate, 145mM NaCl, pH 7.3.

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Complement factor H (fH) is an essential regulatory component of the alternative pathway of complement. It is critical for prevention of complement activation on host cells and tissues, especially the kidney. It has two functional activities: 1) it controls the formation and decay of the alternative pathway C3/C5 convertase (decay accelerating activity) and 2) it acts as a cofactor for factor I which proteolytically inactivates C3b when C3b is bound to factor H (cofactor activity).

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Availability: In stock

Price: £260.41
Size: 250 ug
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