Factor VIII antibody (10R-F102b)

Mouse monoclonal Factor VIII antibody

Synonyms Monoclonal Factor VIII antibody, Anti-Factor VIII antibody, Complement Factor VIII antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications User optimized
Immunogen Factor VIII antibody was raised in mouse using human factor VIII as the immunogen.

Specifications

Host Mouse
Clone 8A
Form & Buffer 10mM Na3PO4, 0.15M NaCl, 0.01% NaN3, pH 7.4.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a well known recessive X-linked coagulation disorder. The Factor VIII gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events.

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Availability: In stock

Price: £304.07
Size: 500 ug
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