FADD protein (His tag) (80R-1206)
Purified recombinant Human FADD protein
|Synonyms||Growth inhibiting gene 3 protein protein, , Fas associating protein protein, Mediator of receptor induced toxicity protein, Fas TNFRSF6 associated via death domain protein, MGC8528 protein, Fas associating protein with death domain protein, GIG3 protein, GIG 3 protein, Fas associated via death domain protein, Fas-associated death domain FADD protein protein, Fas (TNFRSF6) associated via death domain protein, MORT 1 protein, MORT1 protein, Fas associating death domain containing protein protein, Fas-associated via death domain protein, H sapiens mRNA for mediator of receptor induced toxicity protein|
Coomassie Blue stained SDS-PAGE of FADD protein (His tag) (80R-1206)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-208 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS|
|Grade & Purity||> 95% pure|
|Molecular Weight||27.4 kDa (244aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. Recombinant FADD protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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