FGFR2 antibody (70R-9972)
Affinity purified rabbit polyclonal FGFR2 antibody
|Synonyms||Polyclonal FGFR2 antibody, Anti-FGFR2 antibody, FGFR-2, FGFR 2, FLJ98662 antibody, ECT1 antibody, K-SAM antibody, TK14 antibody, CFD1 antibody, CD332 antibody, TK25 antibody, BEK antibody, FGFR 2 antibody, FGFR2, CEK3 antibody, fibroblast growth factor receptor 2 antibody, KGFR antibody, FGFR-2 antibody, JWS antibody, BFR-1 antibody|
|Immunogen||FGFR2 antibody was raised in rabbit using the C terminal of FGFR2 as the immunogen|
|Assay Information||FGFR2 Blocking Peptide, catalog no. 33R-4588, is also available for use as a blocking control in assays to test for specificity of this FGFR2 antibody|
Western Blot analysis using FGFR2 antibody (70R-9972)
FGFR2 antibody (70R-9972) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform.|
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