GADD45G protein (30R-1226)

Purified recombinant Human GADD45G protein

Synonyms GRP17, Growth arrest and DNA damage inducible gamma protein, DDIT2 protein, Growth arrest and DNA-damage-inducible gamma protein, GADD45G protein, Growth arrest and DNA-damage-inducible gamma protein, CR6 protein, Cytokine responsive protein CR6 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of GADD45G protein (30R-1226)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-159 amino acids: MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 17.8 kDa (160 aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl, pH 7.5.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance GADD45G is a member of GADD45 family (GADD45alpha, beta, and gamma) that are nuclear proteins with interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Recombinant GADD45G protein was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of GADD45G protein (30R-1226) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £200.31
Size: 100 ug
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