gamma Synuclein antibody (20R-1009)
Rabbit polyclonal gamma Synuclein antibody
|Synonyms||Polyclonal gamma Synuclein antibody, Anti-gamma Synuclein antibody, Breast cancer specific protein 1 antibody, Persyn antibody, gamma (breast cancer-specific protein 1) BCSG 1 antibody, gamma-synuclein antibody, SNCG protein antibody, PRSN antibody, Breast cancer specific gene 1 protein antibody, PERSYN antibody, Breast cancer-specific gene 1 protein antibody, Breast cancer specific gene 1 antibody, gamma-Synuclein antibody, Gamma synuclein antibody, gamma synuclein antibody, SR antibody, BCSG1 antibody, Synoretin antibody, SNCG antibody, Synuclein antibody, SR antibody, Synuclein gamma antibody|
|Cross Reactivity||To be determined by end-user.|
|Immunogen||gamma Synuclein antibody was raised in Rabbit using recombinant human gamma-Synuclein (1-127aa) as the immunogen.|
Western Blot analysis of Gamma Synuclein antibody (20R-1009)
The recombinant synuclein family (alpha-beta- and gamma-) and the extracts of HT-29 (colon adenocarcinoma) cells were resolved by SDS-PAGE, transferred to PVDF membrane and probed with polyclonal anti-human gamma-synuclein (1:1,000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and the ECL detection system.
|Method of Purification||gamma Synuclein antibody was purified by protein-A affinity chromatography|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.|
Usage & Assay Information
|Usage Recommendations||WB: 1:500-1:2,000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins have in common a highly conserved alpha-helical lipid-binding motif with similarity to the class-A2 lipid-binding domains of the exchangeable apolipoproteins. Although they are homologous, each synuclein is encoded by a different gene on chromosomes 4q21.3-q22. gamma-Synuclein (also called BCSG-1) is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer.|
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