GDF15 protein (His tag) (80R-1209)

Purified recombinant Human GDF15 protein

Synonyms GDF 15, GDF15, PTGFB protein, GDF 15 protein, NSAID protein, NAG1 protein, PTGF beta protein, Growth/differentiation factor 15 protein, NRG 1 protein, Placental TGF beta protein, GDF-15 protein, GDF-15 protein, NAG-1 protein, NAG 1 protein, Placental bone morphogenic protein protein, NRG1 protein, GDF 15 protein, MIC 1 protein, Growth differentiation factor 15 NSAID regulated protein 1 protein, GDF-15, Placental bone morphogenetic protein protein, Macrophage inhibitory cytokine 1 protein, Prostate differentiation factor protein, PLAB protein, MIC1 protein, MIC-1 protein, PDF protein, PTGFB., NSAID (nonsteroidal anti inflammatory drug) activated protein 1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of GDF15 protein (His tag) (80R-1209)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 195-308 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMARA RNGDHCPLGP GRCCRLHTVR ASLEDLGWAD WVLSPREVQV TMCIGACPSQ FRAANMHAQI KTSLHRLKPD TVPAPCCVPA SYNPMVLIQK TDTGVSLQTY DDLLAKDCHC I
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 16.7 kDa (151aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method )

General Information

Biological Significance Growth differentiation factor 15 (GDF-15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. This protein is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

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Images

  • Coomassie Blue stained SDS-PAGE of GDF15 protein (His tag) (80R-1209) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £412.64
Size: 100 ug
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