HEXA antibody (70R-10239)

Affinity purified rabbit polyclonal HEXA antibody

Synonyms Polyclonal HEXA antibody, Anti-HEXA antibody, hexosaminidase A, alpha polypeptide antibody, MGC99608 antibody, TSD antibody
Cross Reactivity Human
Applications WB
Immunogen HEXA antibody was raised in rabbit using the C terminal of HEXA as the immunogen
Assay Information HEXA Blocking Peptide, catalog no. 33R-9958, is also available for use as a blocking control in assays to test for specificity of this HEXA antibody

Images

Western Blot analysis using HEXA antibody (70R-10239)

Western Blot showing HEXA antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

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Images

  • Western Blot analysis using HEXA antibody (70R-10239) | Western Blot showing HEXA antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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