HK1 antibody (70R-10229)

Affinity purified rabbit polyclonal HK1 antibody

Synonyms Polyclonal HK1 antibody, Anti-HK1 antibody, HKI antibody, HK 1 antibody, HK1-tc antibody, HXK1 antibody, hexokinase 1 antibody, HK1-ta antibody, HK1-tb antibody, HK-1, HK 1, HK1, HK-1 antibody
Cross Reactivity Human
Applications WB
Immunogen HK1 antibody was raised in rabbit using the middle region of HK1 as the immunogen
Assay Information HK1 Blocking Peptide, catalog no. 33R-4063, is also available for use as a blocking control in assays to test for specificity of this HK1 antibody

Images

Western Blot analysis using HK1 antibody (70R-10229)

Western Blot showing HK1 antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.

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Images

  • Western Blot analysis using HK1 antibody (70R-10229) | Western Blot showing HK1 antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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