HSBP1 protein (30R-1018)
Purified recombinant Human HSBP1 protein
|Synonyms||NPC A 13 protein, HSF1BP protein, Nasopharyngeal carcinoma associated protein 13 protein, HSBP -1, Heat shock factor binding protein 1 protein, Nasopharyngeal carcinoma-associated protein 13 protein, NPC-A-13 protein, Heat shock factor-binding protein 1 protein, HSBP 1 protein, HSBP -1 protein, HSBP1, NPCA 13 protein, NPC-A-13 protein, , HSBP 1|
Coomassie Blue stained SDS-PAGE of HSBP1 protein (30R-1018)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS|
|Grade & Purity||> 95% pure|
|Molecular Weight||8.5 kDa (76aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 50mM NaCl, 1mM DTT, and 20% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity. This protein was overexpressed in E. coli and was purified to apparent homogeneity by using conventional column chromatography techniques.|
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