HSV2 gD antibody (10C-CR2122M1)

Mouse monoclonal HSV2 gD antibody

Synonyms Monoclonal HSV2 gD antibody, Anti-HSV2 gD antibody, HSV-2 antibody, HSV 2, HSV 1 gD antibody, HSV 2 antibody, HSV-2, Herpes Simplex Virus 1 glycoprotein D antibody, HSV-2 gD antibody, HSV2
Specificity HSV 2
Cross Reactivity This antibody recognizes the gD antigen of HSV 2
Applications ELISA, IF, WB
Immunogen HSV2 gD antibody was raised in mouse using HSV2 as the immunogen.

Specifications

Host Mouse
Clone 1916510
Isotype IgG1
Grade & Purity > 90% pure
Form & Buffer Purified IgG fraction in 10mM PBS, pH 7.2, with 10 mg/ml BSA, and 0.1% NaN3.
Concentration Batch dependent

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.

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Availability: In stock

Price: £212.33
Size: 100 ug
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