IFN gamma antibody (10R-I101B)

Mouse monoclonal IFN gamma antibody

Synonyms Monoclonal IFN gamma antibody, Anti-IFN gamma antibody, Immune Interferon antibody, T cell interferon antibody, Interferon gamma antibody, type II interferon antibody, IFN g antibody, MAF antibody, IFN-g antibody
Specificity Human IFN-gamma
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen IFN gamma antibody was raised in mouse using highly pure recombinant human IFN-gamma as the immunogen.
Assay Information Can be used as a detection antibody with 10R-I101c as the capture antibody in ELISA

Specifications

Host Mouse
Clone M912269
Isotype IgG1 kappa
Molecular Weight 15.6 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS.

Usage & Assay Information

Usage Recommendations ELISA: 4-8 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells.

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IFN gamma antibody

Mouse monoclonal IFN gamma antibody

Availability: In stock

Price: £180.28
Size: 500 ug
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