IGF1 antibody (70R-IG022)

Affinity purified Goat polyclonal IGF1 antibody

Synonyms Polyclonal IGF1 antibody, Anti-IGF1 antibody, Somatamedin C antibody, IGF-1 antibody, IGF1, IGF-1 antibody, IGF 1, IGF-IA antibody, Insulin-like Growth Factor-I antibody, IGF 1 antibody, IGF-1
Specificity Murine IGF1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IGF1 antibody was raised in goat using highly pure recombinant murine IGF-I as the immunogen.

Specifications

Host Goat
Molecular Weight 7.6 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 12-14 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor.

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Availability: In stock

Price: £180.28
Size: 50 ug
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