IGSF8 antibody (70R-9919)
Affinity purified rabbit polyclonal IGSF8 antibody
|Synonyms||Polyclonal IGSF8 antibody, Anti-IGSF8 antibody, IGSF 8 antibody, CD81P3 antibody, PGRL antibody, CD316 antibody, EWI2 antibody, immunoglobulin superfamily, IGSF-8, IGSF8, IGSF-8 antibody, member 8 antibody, IGSF 8|
|Immunogen||IGSF8 antibody was raised in rabbit using the middle region of IGSF8 as the immunogen|
|Assay Information||IGSF8 Blocking Peptide, catalog no. 33R-4805, is also available for use as a blocking control in assays to test for specificity of this IGSF8 antibody|
Western Blot analysis using IGSF8 antibody (70R-9919)
IGSF8 antibody (70R-9919) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.|
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