IL1 alpha protein (30R-AI138)

Purified recombinant Rat IL1 alpha protein

Synonyms Leukocyte Endogenous Mediator protein, Lymphocyte-activating factor protein, IL-1 protein, Interleukin 1 alpha protein, MCF protein, Mononuclear Cell Factor protein, IL 1 protein, IL1, IL-1 alpha protein, EP protein, LEM protein, Endogenous Pyrogen protein, Hematopoietin-1 protein, LAF protein, IL-1, IL 1
Species Rat
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL1 alpha protein corresponding to amino acids MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 17.7 kDa
Form & Buffer Supplied as a lyophilized powder from 10 mM sodium phosphate, pH 8.0, 50 mM NaCl.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent proliferation of Mouse D10S cells is 2 x 10^8 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: £180.28
Size: 10 ug
OR
Shipping
View Our Distributors