IL1 beta protein (His tag) (80R-1044)

Purified recombinant Mouse IL1 beta protein

Synonyms IFN beta inducing factor protein, Interleukin 1 beta Catabolin protein, IL-1 beta protein, Mouse IL1 beta protein, IL 1B protein, Preinterleukin beta protein, Interleukin 1 beta precursor protein, LAF protein, IL1F2 protein, IL1B protein, IL beta-1, H1 protein, IL 1 beta protein, IL-1b protein, Hematopoietin 1 protein, IL-1beta protein, OAF protein, IL1 beta, IL beta 1, Osteoclast activating factor protein, Pro interleukin 1 beta, IL beta 1 protein, IL beta-1 protein, IL 1 protein, Interleukin 1 beta protein
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of IL1 beta protein (His tag) (80R-1044)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 118-269 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 21 kDa (189aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL-1 beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1 beta is required for tumor growth, metastasis, and angiogenesis in several animal models. Recombinant mouse IL-1 beta, fused to His tag, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of IL1 beta protein (His tag) (80R-1044) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £204.32
Size: 100 ug
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