IL10 protein (30R-AI075)

Purified recombinant Human IL10 protein

Synonyms CSIF protein, B-TCGF protein, TGIF protein, IL 10 protein, Interleukin 10 protein, IL-10 protein, IL10, IL 10, IL-10 protein, IL-10
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL10 protein corresponding to amino acids SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 18.7 kDa
Form & Buffer Lyophilized from 20mM Na3PO4, pH 7.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is less than 10ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL10 inhibits the expression of proinflammatory cytokines such as IL1 and TNFa. Like IL4, IL10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL10 active on Mouse cells, but Mouse IL10 is inactive on human cells.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: £180.28
Size: 10 ug
OR
Shipping
View Our Distributors