IL12 protein (30R-AI006)

Purified recombinant Human IL12 protein

Synonyms NKSF protein, IL-12, Cytotoxic lymphocyte maturation factor protein, IL-12 protein, TSF protein, IL 12, CLMF protein, Interleukin 12 protein, IL 12 protein, CTL maturation factor protein, TCMF protein, IL-12 protein, IL12
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL12 protein corresponding to amino acids RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS.
Expression System CHO cells
Grade & Purity > 98% pure
Molecular Weight 75 kDa
Form & Buffer Lyophilized from 0.5 x PBS, pH 7.2. Reconstitute in 1xPBS to a concentration of 0.2 mg/ml.

Usage & Assay Information

Bioactivity The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is approximately 1.0 ng/ml, corresponding to a specific activity of approximately 1 x 10^6 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells.

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Availability: In stock

Price: £180.28
Size: 10 ug
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