IL13 antibody (70R-IR012)

Affinity purified Rabbit polyclonal IL13 antibody

Synonyms Polyclonal IL13 antibody, Anti-IL13 antibody, IL-13 antibody, IL-13 antibody, NC300 antibody, IL13, Interleukin 13 antibody, IL 13, Human P600 antibody, IL 13 antibody, IL-13
Specificity Human IL-13
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IL13 antibody was raised in rabbit using highly pure recombinant human IL-13 as the immunogen.

Specifications

Host Rabbit
Molecular Weight 12.3 kDa (predicted detection band MW)
Form & Buffer Lyophilized from 0.5x PBS, pH 7.4.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.12-0.15 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma. Human and Mouse IL13 is cross-species reactive.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: £220.34
Size: 100 ug
OR
Shipping
View Our Distributors