IL17A protein (Mouse) (30R-AI136)

Purified recombinant Mouse IL17A protein

Synonyms ILA 17 protein, Interleukin 17A protein, IL-17A protein, IL-17 protein, CTLA-8 protein, ILA-17 protein, ILA-17, ILA 17, IL17A
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL17A protein corresponding to amino acids MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 30 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Measured by its ability to induce IL-6 production by NIH 3T3 cells.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance The originally described IL17 protein, now known as IL17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.

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Availability: In stock

Price: £180.28
Size: 25 ug
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