IL1b antibody (10R-I155A)

Mouse monoclonal IL1b antibody

Synonyms Monoclonal IL1b antibody, Anti-IL1b antibody, IL-1b, IL 1b antibody, IL-1b antibody, IL 1b, IL-1b antibody, IL1 beta antibody, IL1b, Interlekin 1 beta antibody
Specificity Human IL1b
Applications ELISA, FC, IHC, WB
Immunogen IL1b antibody was raised in mouse using E. Coli-derived recombinant human IL1 beta/IL1F2 as the immunogen.

Specifications

Host Mouse
Clone 9627
Isotype IgG1
Form & Buffer Supplied as a lyophilized powder. Reconstitute with PBS buffer.

Usage & Assay Information

Usage Recommendations ELISA: 2-8 ug/ml, IHC: 15 ug/ml, WB: 1 ug/ml,

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL1 is a name that designates two pleiotropic cytokines, IL1 alpha (IL1F1) and IL1Beta (IL1F2), which are the products of distinct genes. IL1 alpha and IL1Beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1 alpha and IL1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL1 RI binds directly to IL1 alpha or IL1Beta and then associates with IL1R accessory protein (IL1R3/IL1R AcP) to form a highaffinity receptor complex that is competent for signal transduction.

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Availability: In stock

Price: £444.69
Size: 500 ug
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