IL22 protein (30R-AI117)

Purified recombinant Human IL22 protein

Synonyms IL 22 protein, Interleukin 22 protein, IL22, IL-22 protein, IL-22, IL-TIF protein, IL 22, IL-22 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL22 protein corresponding to amino acids MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 33.6 kDa
Form & Buffer Supplied as lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to activate STAT following receptor ligand interaction.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL22 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL22 inhibits IL4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL22 signals through a receptor system consisting of IL10R-beta/CRF2-4 and IL22R, both of which are members of the class II cytokine-receptor family.

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Availability: In stock

Price: £180.28
Size: 10 ug
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