IL4 antibody (70R-IR046)

Affinity purified Rabbit polyclonal IL4 antibody

Synonyms Polyclonal IL4 antibody, Anti-IL4 antibody, IL-4 antibody, IL-4, IL 4 antibody, B cell stimulating factor antibody, BCGF antibody, BSF-1 antibody, BCDF antibody, Interleukin 4 antibody, IL-4 antibody, IL 4, IL4
Specificity Human IL-4
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IL4 antibody was raised in rabbit using highly pure recombinant human IL-4 as the immunogen.

Specifications

Host Rabbit
Molecular Weight 14 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.03-0.05 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes.

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Availability: In stock

Price: £180.28
Size: 50 ug
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