IRF1 protein (His tag) (80R-1026)
Purified recombinant Human IRF1 protein
|Synonyms||IRF-1, Interferon regulatory factor 1 protein, Interferon regulatory factor-1 Interferon regulatory factor 1 protein, IRF 1, IRF1, IRF 1 protein, IRF 1 protein, IRF-1 protein, IRF-1 protein, IRF1 protein, MAR1., MAR protein|
Coomassie Blue stained SDS-PAGE of IRF1 protein (His tag) (80R-1026)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-114 amino acids: MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP|
|Grade & Purity||> 90% pure|
|Molecular Weight||15 kDa (134 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques.|
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