IRF1 protein (His tag) (80R-1026)

Purified recombinant Human IRF1 protein

Synonyms IRF-1, Interferon regulatory factor 1 protein, Interferon regulatory factor-1 Interferon regulatory factor 1 protein, IRF 1, IRF1, IRF 1 protein, IRF 1 protein, IRF-1 protein, IRF-1 protein, IRF1 protein, MAR1., MAR protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of IRF1 protein (His tag) (80R-1026)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-114 amino acids: MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 15 kDa (134 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of IRF1 protein (His tag) (80R-1026) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £204.32
Size: 100 ug
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