IRF3 protein (30R-1090)
Purified recombinant Human IRF3 protein
|Synonyms||IRF3 protein, IRF 3, IRF-3, IRF 3., IRF-3 protein, Interferon regulatory factor-3 protein, IRF-3 protein, Interferon regulatory factor 3 protein, IRF3, IRF 3 protein|
Coomassie Blue stained SDS-PAGE of IRF3 protein (30R-1090)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-112 amino acids: MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NS|
|Grade & Purity||> 95% pure|
|Molecular Weight||13.0 kDa (112aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. Recombinant human IRF3 was expressed in E. coli and purified by using conventional chromatography techniques|
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