KCNN3 antibody (70R-5182)

Rabbit polyclonal KCNN3 antibody raised against the C terminal of KCNN3

Synonyms Polyclonal KCNN3 antibody, Anti-KCNN3 antibody, KCNN3, KCNN-3 antibody, KCNN-3, KCNN 3, KCNN 3 antibody, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 antibody
Specificity KCNN3 antibody was raised against the C terminal of KCNN3
Cross Reactivity Human, Mouse, Rat, Dog
Applications WB
Immunogen KCNN3 antibody was raised using the C terminal of KCNN3 corresponding to a region with amino acids ITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSA
Assay Information KCNN3 Blocking Peptide, catalog no. 33R-4172, is also available for use as a blocking control in assays to test for specificity of this KCNN3 antibody

Images

Western Blot analysis using KCNN3 antibody (70R-5182)

KCNN3 antibody (70R-5182) used at 2 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 81 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of KCNN3 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

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Images

  • Western Blot analysis using KCNN3 antibody (70R-5182) | KCNN3 antibody (70R-5182) used at 2 ug/ml to detect target protein.

Availability: In stock

Price: £250.71
Size: 50 ug
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