KCNQ2 antibody (70R-5181)

Rabbit polyclonal KCNQ2 antibody raised against the N terminal of KCNQ2

Synonyms Polyclonal KCNQ2 antibody, Anti-KCNQ2 antibody, KCNA11 antibody, EBN1 antibody, Potassium Voltage-Gated Channel Kqt-Like Subfamily Member 2 antibody, EBN antibody, KVEBN1 antibody, KCNQ-2 antibody, KCNQ 2 antibody, HNSPC antibody, KV7.2 antibody, KCNQ2, BFNC antibody, ENB1 antibody, KCNQ-2, KCNQ 2
Specificity KCNQ2 antibody was raised against the N terminal of KCNQ2
Cross Reactivity Human,Mouse,Rat,Dog
Applications WB
Immunogen KCNQ2 antibody was raised using the N terminal of KCNQ2 corresponding to a region with amino acids YRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFL
Assay Information KCNQ2 Blocking Peptide, catalog no. 33R-10224, is also available for use as a blocking control in assays to test for specificity of this KCNQ2 antibody

Images

Western Blot analysis using KCNQ2 antibody (70R-5181)

KCNQ2 antibody (70R-5181) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 93 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of KCNQ2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).

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Images

  • Western Blot analysis using KCNQ2 antibody (70R-5181) | KCNQ2 antibody (70R-5181) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: £250.71
Size: 50 ug
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