KIR2DL1 protein (30R-1030)
Purified recombinant Human KIR2DL1 protein
|Synonyms||KIR2, Killer cell immunoglobulin-like receptor 2DL1 protein, Natural killer associated transcript 1 protein, Killer cell immunoglobulin-like receptor 2DL1 Killer cell immunoglobulin like receptor 2DL1 protein, KIR-2, p58.1 MHC class-I-specific NK receptor protein, MHC class I NK cell receptor protein, KIR 2 protein, NKAT 1 protein, p58 NK receptor protein, CD158A protein, KIR 2, KIR-2 protein, NKAT1 protein, p58 NK receptor protein, p58.1 MHC class I specific NK receptor, NKAT-1 protein, p58 natural killer cell receptor clones CL-42/47.11 protein, KIR2DL1 (p58 KIR protein, CD158) protein, MHC class I NK cell receptor protein, Natural killer-associated transcript 1 protein, KIR2DL1 protein|
Coomassie Blue stained SDS-PAGE of KIR2DL1 protein (30R-1030)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MEGVHRKPSL LAHPGRLVKS EETVILQCWS DVMFEHFLLH REGMFNDTLR LIGEHHDGVS KANFSISRMT QDLAGTYRCY GSVTHSPYQV SAPSDPLDIV IIGLYEKPSL SAQLGPTVLA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAGPKVNGTF QADFPLGPAT HGGTYRCFGS FHDSPYEWSK SSDPLLVSVT GN|
|Grade & Purity||> 95% pure|
|Molecular Weight||22.2 kDa|
|Form & Buffer||Supplied as a liquid in 20 mM Tris-HCl buffer, pH7.5.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||An inhibitory Keller Cell Ig-like Receptor(KIR, previously called p58 KIR, p58.1, cl-42, NKAT1, or KIR-K6), which recognizes class I MHC molecules(HLA-Cw2, -Cw4, -Cw5, and Cw6). The protein coding region of the extracellular domain of KIR2DL1(amino acids 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DL1 was overexpressed as insoluble protein aggregates(inclusion bodies). The recombinant KIR2DL1 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.|
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