KPNB1 antibody (70R-10262)

Affinity purified rabbit polyclonal KPNB1 antibody

Synonyms Polyclonal KPNB1 antibody, Anti-KPNB1 antibody, importin beta 1 antibody, MGC2157 antibody, karyopherin, KPNB 1, NTF97 antibody, IPOB antibody, IMB1 antibody, KPNB-1, Impnb antibody, MGC2156 antibody, IPO1 antibody, KPNB1, MGC2155 antibody, KPNB 1 antibody, KPNB-1 antibody
Cross Reactivity Human
Applications WB
Immunogen KPNB1 antibody was raised in rabbit using the N terminal of KPNB1 as the immunogen
Assay Information KPNB1 Blocking Peptide, catalog no. 33R-2454, is also available for use as a blocking control in assays to test for specificity of this KPNB1 antibody

Images

Western Blot analysis using KPNB1 antibody (70R-10262)

Western Blot showing KPNB1 antibody used at a concentration of 1 ug/ml against ACHN Cell Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using KPNB1 antibody (70R-10262) | Western Blot showing KPNB1 antibody used at a concentration of 1 ug/ml against ACHN Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
OR
Shipping
View Our Distributors