KRAS protein (His tag) (80R-1372)

Purified recombinant Human KRAS protein

Synonyms GTPase Kras protein, , C-K-RAS protein, NS3 protein, RASK2 protein, K RAS4B protein, KRAS1 protein, K-RAS4A protein, K-RAS2A protein, K-RAS4B protein, NS 3 protein, K RAS4A protein, K-RAS2B protein, K-RAS2A protein, KRAS 1 protein, KI-RAS protein, K RAS2B protein, KI RAS protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of KRAS protein (His tag) (80R-1372)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-185 amino acids: MGSSHHHHHH SSGLVPRGSH MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKC
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 23.2 kDa (205aa) confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl,1mM DTT and 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of KRAS protein (His tag) (80R-1372) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £236.37
Size: 100 ug
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