Leptin protein (30R-AL001)

Purified recombinant Human Leptin protein

Synonyms Obesity protein, OB protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Leptin protein corresponding to amino acids MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 16.2 kDa
Form & Buffer Lyophilized from 0.1% TFA. Reconstitute in water to a concentration of 1.0-5.0 mg/ml.

Usage & Assay Information

Bioactivity PeproTech's Mouse Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 ug Leptin/gm of body weight for 14 days. Sign

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models.

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Availability: In stock

Price: £180.28
Size: 1 mg
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