LIGHT antibody (70R-LR014)

Affinity purified Rabbit polyclonal LIGHT antibody

Synonyms Polyclonal LIGHT antibody, Anti-LIGHT antibody, TNF14 antibody, CD258 antibody, HVEM-L antibody, TNFSF14 antibody, Ligand for herpesvirus entry mediator antibody
Specificity Human LIGHT
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen LIGHT antibody was raised in rabbit using highly pure recombinant human LIGHT as the immunogen.

Specifications

Host Rabbit
Molecular Weight 20.1 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

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Availability: In stock

Price: £180.28
Size: 50 ug
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