LOXL3 antibody (70R-10022)
Affinity purified rabbit polyclonal LOXL3 antibody
|Synonyms||Polyclonal LOXL3 antibody, Anti-LOXL3 antibody, LOXL 3, lysyl oxidase-like 3 antibody, LOXL 3 antibody, LOXL-3, LOXL3, LOXL antibody, LOXL-3 antibody|
|Immunogen||LOXL3 antibody was raised in rabbit using the middle region of LOXL3 as the immunogen|
|Assay Information||LOXL3 Blocking Peptide, catalog no. 33R-1049, is also available for use as a blocking control in assays to test for specificity of this LOXL3 antibody|
Western Blot analysis using LOXL3 antibody (70R-10022)
Western Blot showing LOXL3 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.|
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