MAGEL2 antibody (70R-9924)
Affinity purified rabbit polyclonal MAGEL2 antibody
|Synonyms||Polyclonal MAGEL2 antibody, Anti-MAGEL2 antibody, MAGEL 2 antibody, nM15 antibody, MAGE-like 2 antibody, MAGEL 2, MAGEL-2, MAGEL-2 antibody, NDNL1 antibody, MAGEL2|
|Immunogen||MAGEL2 antibody was raised in rabbit using the C terminal of MAGEL2 as the immunogen|
|Assay Information||MAGEL2 Blocking Peptide, catalog no. 33R-6559, is also available for use as a blocking control in assays to test for specificity of this MAGEL2 antibody|
Western Blot analysis using MAGEL2 antibody (70R-9924)
MAGEL2 antibody (70R-9924) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product