Mannose 6-Phosphate Receptor antibody (10R-M105a)

Mouse monoclonal Mannose 6-Phosphate Receptor antibody

Synonyms Monoclonal Mannose 6-Phosphate Receptor antibody, Anti-Mannose 6-Phosphate Receptor antibody, Mannose-Phosphate Receptor-6 antibody, Mannose 6-Phosphate Receptor, Mannose-Phosphate Receptor 6, Late Endosome Marker, Mannose 6 Phosphate Receptor (Cation independent) antibody, Mannose-Phosphate Receptor 6 antibody, Mannose-Phosphate Receptor-6
Specificity Bovine
Cross Reactivity Human, non-human primate, rat
Applications ICC, IF, IP, WB
Immunogen Mannose 6-phosphate receptor antibody was raised in mouse using purified Bovine 300 kDa CI-MPR. as the immunogen.

Images

Immunofluorescent staining using Mannose 6-Phosphate Receptor antibody (10R-M105a)

Specifications

Host Mouse
Clone 2G11
Isotype IgG2a
Form & Buffer PBS solution containing 0.05% NaN3
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ICC: 2-5 ug/ml, IF: 2-5 ug/ml, WB: 1 ug/ml

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Lysosomal enzymes containing one or two mannose 6-phosphate (man6P) moieties are moved about in the cell by means of ~300 kDa cation independent mannose 6-phospate receptors (CI-MPR). In addition to its man6P binding activity, the MPR contains a separate binding site for the type II insulin-like growth factor and is capable of binding both man6P and IGF-II simultaneously. An ~240 kDa soluble, truncated form, representing the extracellular domain of the protein, has also been found circulating in serum and is capable of binding both ligands.

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Images

  • Immunofluorescent staining using Mannose 6-Phosphate Receptor antibody (10R-M105a) |

Availability: In stock

Price: £500.78
Size: 100 ug
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