MCM2 antibody (70R-1613)

Rabbit polyclonal MCM2 antibody raised against the N terminal of MCM2

Synonyms Polyclonal MCM2 antibody, Anti-MCM2 antibody, MCM 2 antibody, MCM-2 antibody, Minichromosome Maintenance Complex Component 2 antibody, MCM-2, MCM 2, MCM2
Specificity MCM2 antibody was raised against the N terminal of MCM2
Cross Reactivity Human
Applications WB
Immunogen MCM2 antibody was raised using the N terminal of MCM2 corresponding to a region with amino acids PGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGM
Assay Information MCM2 Blocking Peptide, catalog no. 33R-7129, is also available for use as a blocking control in assays to test for specificity of this MCM2 antibody

Images

Western Blot analysis using MCM2 antibody (70R-1613)

MCM2 antibody (70R-1613) used at 1.25 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 99 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of MCM2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

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Images

  • Western Blot analysis using MCM2 antibody (70R-1613) | MCM2 antibody (70R-1613) used at 1.25 ug/ml to detect target protein.

Availability: In stock

Price: £220.34
Size: 100 ug
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