MED4 protein (His tag) (80R-1316)
Purified recombinant Human MED4 protein
|Synonyms||MED-4 protein, MED 4 protein, Mediator complex subunit 4 Activator-recruited cofactor 36 kDa component protein, MED 4, DRIP36 protein, Mediator of RNA polymerase II transcription subunit 4 protein, ARC36 protein, HSPC126 protein, MED-4, VDRIP protein, Vitamin D3 receptor-interacting protein complex 36 kDa component., TRAP/SMCC/PC2 subunit p36 subunit protein, MED4|
Coomassie Blue stained SDS-PAGE of MED4 protein (His tag) (80R-1316)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-270 amino acids: MAASSSGEKE KERLGGGLGV AGGNSTRERL LSALEDLEVL SRELIEMLAI SRNQKLLQAG EENQVLELLI HRDGEFQELM KLALNQGKIH HEMQVLEKEV EKRDGDIQQL QKQLKEAEQI LATAVYQAKE KLKSIEKARK GAISSEEIIK YAHRISASNA VCAPLTWVPG DPRRPYPTDL EMRSGLLGQM NNPSTNGVNG HLPGDALAAG RLPDVLAPQY PWQSNDMSMN MLPPNHSSDF LLEPPGHNKE DEDDVEIMST DSSSSSSESD LEHHHHHH|
|Grade & Purity||> 80% pure|
|Molecular Weight||30.7 kDa (278aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 1mM DTT and 100mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Mediator complex subunit 4 (MED4) is also known as mediator of RNA polymerase II transcription subunit 4 or vitamin D3 receptor-interacting protein complex 36 kDa component (DRIP36). This protein is a component of the vitamin D receptor-interacting protein (DRIP) complex which functions as a nuclear receptor coactivator. The DRIP complex is capable of activating nuclear receptors in a ligand-dependent manner. Recombinant human MED4, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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