MGST1 antibody (70R-10041)
Affinity purified rabbit polyclonal MGST1 antibody
|Synonyms||Polyclonal MGST1 antibody, Anti-MGST1 antibody, MGST 1 antibody, MGST1, MGST 1, GST12 antibody, MGC14525 antibody, MGST-1 antibody, MGST antibody, MGST-1, MGST-I antibody, microsomal glutathione S-transferase 1 antibody|
|Immunogen||MGST1 antibody was raised in rabbit using the N terminal of MGST1 as the immunogen|
|Assay Information||MGST1 Blocking Peptide, catalog no. 33R-6812, is also available for use as a blocking control in assays to test for specificity of this MGST1 antibody|
Western Blot analysis using MGST1 antibody (70R-10041)
MGST1 antibody (70R-10041) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. MGST1 catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.|
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