MOBKL1B protein (His tag) (80R-1625)
Purified recombinant Human MOBKL1B protein
|Synonyms||Mps one binder kinase activator-like 1B protein, FLJ11595 protein, MOBKLB 1, MATS1 protein, MOBKLB-1, MOBK1B, C2orf6 protein, MOBKLB 1 protein, Mob4B protein, MOBKLB-1 protein, MOBKL1B, MOB1 protein, FLJ10788 protein|
Coomassie Blue stained SDS-PAGE of MOBKL1B protein (His tag) (80R-1625)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-216 amino acids: MGSSHHHHHH SSGLVPRGSH MSFLFSSRSS KTFKPKKNIP EGSHQYELLK HAEATLGSGN LRQAVMLPEG EDLNEWIAVN TVDFFNQINM LYGTITEFCT EASCPVMSAG PRYEYHWADG TNIKKPIKCS APKYIDYLMT WVQDQLDDET LFPSKIGVPF PKNFMSVAKT ILKRLFRVYA HIYHQHFDSV MQLQEEAHLN TSFKHFIFFV QEFNLIDRRE LAPLQELIEK LGSKDR|
|Grade & Purity||> 95% pure|
|Molecular Weight||27.2 kDa (236aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.2M NaCl, 5mM DTT and 30% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||MOBKL1B, also known as MOB1B, belongs to the MOB1/phocein family. It stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1B participates in cell cycle checkpoint control and tumor inhibition. Recombinant human MOBKL1B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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