MUC1 antibody (10R-M129b)

Hamster monoclonal MUC1 antibody

Synonyms Monoclonal MUC1 antibody, Anti-MUC1 antibody, MU 1c, MU-1c antibody, MU-1c, Mucin-1 antibody, MU-1c antibody, MU 1c antibody, MU 1c antibody, MUC1
Cross Reactivity Human, mouse
Applications FC, IF, IHC, IP, WB
Immunogen MUC1 antibody was raised in hamster using a synthetic peptide corresponding to aa 239-255 (SSLSYTNPAVAATSANL) form the cytoplasmic tail of MUC1 as the immunogen.

Images

Immunohistochemical staining using MUC1 antibody (10R-M129b)

Formalin-fixed, paraffin-embedded human breast cancer stained with MUC1 antibody using alkaline phosphatase-conjugate and fast red chromogen. Note nuclear and cytoplasmic staining of tumor cells.

Specifications

Host Hamster
Clone MH1
Isotype IgG
Method of Purification MUC1 antibody was purified by Protein G chromatography.
Form & Buffer 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Muc1 is a heavily O-glycosylated transmembrane protein expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed in >90% breast carcinomas and metastases. In normal mammary gland it is expressed in apical surface of glandular epithelium. In breast cancer Muc1 is overexpressed; is underglycosylated and the apical localization is lost.

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Images

  • Immunohistochemical staining using MUC1 antibody (10R-M129b) | Formalin-fixed, paraffin-embedded human breast cancer stained with MUC1 antibody using alkaline phosphatase-conjugate and fast red chromogen. Note nuclear and cytoplasmic staining of tumor cells.

Availability: In stock

Price: £387.81
Size: 100 ug
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