Neuritin protein (30R-AN048)

Purified recombinant Human/Rat Neuritin protein

Synonyms CPG15 protein, NRN1 protein, Human Neuritin protein, Rat Neuritin protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Neuritin protein corresponding to amino acids MAGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 9.7 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.
Sequence Information Complete identity between mature sequences amongst Human and Rat species for Neuritin.

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Availability: In stock

Price: £180.28
Size: 20 ug
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