NKp46 antibody (10R-1007)

Mouse monoclonal NKp46 antibody

Synonyms Monoclonal NKp46 antibody, Anti-NKp46 antibody, Natural cytotoxicity triggering receptor 1 antibody, hNKp46 antibody, Lymphocyte antigen 94 homolog antibody, NKp46 antibody, NKp-46, NK cell-activating receptor antibody, NK-p46 antibody, CD335 antigen antibody, NKp 46, NKp-46 antibody, NCR1 antibody, NKp46, Natural killer cell p46-related protein antibody, NCR antibody, NKp46 Extracellular Ig-like domain antibody, LY94 antibody, NKp 46 antibody, Natural cytotoxicity triggering receptor 1 isoform a antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, FC, WB
Immunogen NKp46 antibody was raised in mouse using recombinant human Nkp46 (22-255aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone n1D9
Isotype IgG1 kappa
Source Anti-human Nkp46 antibody, clone n1D9, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant Nkp46.
Method of Purification NKp46 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations To be determiend by end-user.

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

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Availability: In stock

Price: £212.33
Size: 100 ul
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