NQO1 antibody (70R-10256)

Affinity purified rabbit polyclonal NQO1 antibody

Synonyms Polyclonal NQO1 antibody, Anti-NQO1 antibody, NMORI antibody, QR1 antibody, NQO-1 antibody, NQO 1 antibody, quinone 1 antibody, NMOR1 antibody, NQO1, DTD antibody, DHQU antibody, NQO-1, NADPH dehydrogenase, NQO 1, DIA4 antibody
Cross Reactivity Human
Applications WB
Immunogen NQO1 antibody was raised in rabbit using the C terminal of NQO1 as the immunogen
Assay Information NQO1 Blocking Peptide, catalog no. 33R-9961, is also available for use as a blocking control in assays to test for specificity of this NQO1 antibody

Images

Western Blot analysis using NQO1 antibody (70R-10256)

Western Blot showing NQO1 antibody used at a concentration of 1 ug/ml against 721_B Cell Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Images

  • Western Blot analysis using NQO1 antibody (70R-10256) | Western Blot showing NQO1 antibody used at a concentration of 1 ug/ml against 721_B Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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