NR3C2 antibody (70R-1003)

Rabbit polyclonal NR3C2 antibody raised against the middle region of NR3C2

Synonyms Polyclonal NR3C2 antibody, Anti-NR3C2 antibody, MLR antibody, NRC2 3, MGC133092 antibody, Nuclear Receptor Subfamily 3 Group C Member 2 antibody, MR antibody, NRC2 3 antibody, NR3C2, NRC2-3, NRC2-3 antibody, MCR antibody
Specificity NR3C2 antibody was raised against the middle region of NR3C2
Cross Reactivity Human
Applications IHC, WB
Immunogen NR3C2 antibody was raised using the middle region of NR3C2 corresponding to a region with amino acids RRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPP
Assay Information NR3C2 Blocking Peptide, catalog no. 33R-8142, is also available for use as a blocking control in assays to test for specificity of this NR3C2 antibody

Images

Western blot analysis using NR3C2 antibody (70R-1003)

Recommended NR3C2 Antibody Titration: 1.25ug/ml

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 107 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of NR3C2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

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Images

  • Western blot analysis using NR3C2 antibody (70R-1003) | Recommended NR3C2 Antibody Titration: 1.25ug/ml
  • Immunohistochemical staining using NR3C2 antibody (70R-1003) | Human Kidney

Availability: In stock

Price: £220.34
Size: 100 ug
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