NRG1 antibody (10R-1112)

Mouse monoclonal NRG1 antibody

Synonyms Monoclonal NRG antibody, Anti-NRG1 antibody, NRG1, HRG antibody, NRG-1, NRG 1 antibody, neuregulin 1 isoform HRG-beta3 antibody, NRG 1, GGF antibody, NDF antibody, neuregulin 1 antibody, NRG-1 antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen NRG1 antibody was raised in mouse using recombinant human NRG1 isoform HRG-beta3 (20-241aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone k1G13
Isotype IgG1 kappa
Source Anti-human NRG1 antibody, clone k1G13, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NRG1 protein.
Method of Purification NRG1 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Neuregulin1 (NRG1) is one of four proteins in the neuregulin family that act on the Epidermal growth factor receptor (EGFR) family of receptors. NRG1 was originally identified as a 44 kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In many brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. This variant (HRG-beta3) of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines.

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Availability: In stock

Price: £212.33
Size: 100 ul
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