Oncostatin M antibody (70R-OR001)

Affinity purified Rabbit polyclonal Oncostatin M antibody

Synonyms Polyclonal Oncostatin M antibody, Anti-Oncostatin M antibody, OSM antibody
Specificity Human oncostatin M
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen Oncostatin M antibody was raised in rabbit using highly pure recombinant human oncostatin M as the immunogen.

Specifications

Host Rabbit
Molecular Weight 23.9 kDa (predicted detection band MW)
Form & Buffer Lyophilized from 0.5x PBS, pH 7.4. Reconstitute in sterile water to a concentration of > 0.2 mg/ml.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.1-0.175 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi?s sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi?s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL6, and CNTF. Human OSM is active on Mouse cells.

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Availability: In stock

Price: £260.41
Size: 100 ug
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