OTC antibody (70R-1117)

Rabbit polyclonal OTC antibody raised against the N terminal of OTC

Synonyms Polyclonal OTC antibody, Anti-OTC antibody, OCTD antibody, Ornithine Carbamoyltransferase antibody
Specificity OTC antibody was raised against the N terminal of OTC
Cross Reactivity Human, Mouse, Rat, Dog
Applications IHC, WB
Immunogen OTC antibody was raised using the N terminal of OTC corresponding to a region with amino acids AFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLSAD
Assay Information OTC Blocking Peptide, catalog no. 33R-1173, is also available for use as a blocking control in assays to test for specificity of this OTC antibody

Images

Western Blot analysis using OTC antibody (70R-1117)

OTC antibody (70R-1117) used at 2.5 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 39 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of OTC antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 2.5 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

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Images

  • Western Blot analysis using OTC antibody (70R-1117) | OTC antibody (70R-1117) used at 2.5 ug/ml to detect target protein.

Availability: In stock

Price: £220.34
Size: 100 ug
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