PCK1 antibody (70R-2484)

Rabbit polyclonal PCK1 antibody

Synonyms Polyclonal PCK1 antibody, Anti-PCK1 antibody, PCK 1, PEPCK-C antibody, PCK 1 antibody, PEPCKC antibody, PEPCK1 antibody, MGC22652 antibody, PCK-1 antibody, PCK-1, Phosphoenolpyruvate Carboxykinase 1 antibody, PCK1
Cross Reactivity Human
Applications WB
Immunogen PCK1 antibody was raised using a synthetic peptide corresponding to a region with amino acids PPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEE
Assay Information PCK1 Blocking Peptide, catalog no. 33R-7272, is also available for use as a blocking control in assays to test for specificity of this PCK1 antibody

Images

Western Blot analysis using PCK1 antibody (70R-2484)

PCK1 antibody (70R-2484) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 69 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of PCK1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance PCK1 is a main control point for the regulation of gluconeogenesis. PCK1, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

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Images

  • Western Blot analysis using PCK1 antibody (70R-2484) | PCK1 antibody (70R-2484) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: £276.43
Size: 50 ug
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