PDCD1 antibody (10R-1072)

Mouse monoclonal PDCD1 antibody

Synonyms Monoclonal PDCD1 antibody, Anti-PDCD1 antibody, PD1 antibody, PDCD 1, CD279 antibody, PDCD-1 antibody, hPD-1 antibody, hPD-l antibody, Programmed cell death 1 antibody, PDCD-1, PDCD 1 antibody, PDCD1, CD279 antigen antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen PDCD1 antibody was raised in mouse using recombinant human PDCD1 (21-167aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 4F12
Isotype IgG2b kappa
Source Anti-human PDCD1 antibody, clone 4F12, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PDCD1 protein.
Method of Purification PDCD1 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases

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Availability: In stock

Price: £208.33
Size: 100 ul
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