PEA15 protein (30R-1399)

Purified recombinant Human PEA15 protein

Synonyms PEA 15 protein, MAT 1 protein, PEA-15, HUMMAT1H protein, PEA 15 protein, PEA15 protein, Phosphoprotein enriched in astrocytes 15 protein, Phosphoprotein enriched in astrocytes protein, PEA15, MAT 1H protein, PEA-15 protein, PEA 15, Phosphoprotein enriched in diabetes., Astrocytic phosphoprotein PEA-15 protein, 15kD Astrocytic phosphoprotein PEA 15 protein, PED protein, HMAT 1 protein, Homolog of mouse MAT1 oncogene protein, Homolog of mouse MAT 1 oncogene protein, MAT1 protein, HMAT1 protein, Astrocytic phosphoprotein PEA15 protein, Phosphoprotein enriched in astrocytes 15kD protein, MAT1H protein, HUMMAT 1H protein, PEA15 protein protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of PEA15 protein (30R-1399)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-130 amino acids: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 15 kDa (130aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 1mM DTT and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Phospho-enriched protein in astrocytes 15 kDa (PEA-15) is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. Recombinant human PEA-15 was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of PEA15 protein (30R-1399) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £412.64
Size: 100 ug
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